Kirkby has a large town centre which includes a Morrisons, shopping parade and covered market, as well as various smaller shopping parades and individual shops throughout the town
Kirkby Town Centre includes Kirkby Shopping Centre which has over 106 indoor units of various sizes, and Kirkby Market which has over 130 covered market stalls.
There are 12 smaller shopping centres around Kirkby which have between 3 and 16 units:
- Broad Lane Shops, Southdene
- Copplehouse Lane Shops, Field Lane Estate
- Glovers Brow Shops, Kirkby Park
- James Holt Avenue Shops, Westvale
- Kennelwood Avenue Shops, Northwood
- Loweswater Way Shops, Towerhill
- Moorfield Shopping Centre, Towerhill
- Old Farm Road Shops, Southdene
- Old Hall Estate Shops, Old Hall Estate
- Park Brow Shops, Southdene
- Quarry Green Shops, Northwood
- Richard Hesketh Drive Shops, Westvale
There are also a small number of individual shops:
- BestOne Shop, Northwood
- J Pope and Sons Farmshop, Melling Mount
- Johnny Todd Off License, Westvale
- Londis at Mount Garage, Melling Mount
- Mace at Westvale Service Station
- MP Food and Wines, Northwood
- Stretford News and Convenience Store, Towerhill
- The Corner Shop, Towerhill
- William Hill, Westvale
There are also a huge number of businesses on Kirkby Industrial Estate, including shops such as:
- Curtis and Bell Stationary